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AstraZeneca vaccine is effective against COVID-19, phase III study says

The results may mean the doses could soon be put into the arms of Americans.

  • By Jaclyn Diaz/NPR
An illustration picture shows vials with Covid-19 Vaccine stickers attached and syringes, with the logo of the University of Oxford and its partner British pharmaceutical company AstraZeneca, on November 17, 2020.

 Justin Tallis / JUSTIN TALLIS/AFP via Getty Images

An illustration picture shows vials with Covid-19 Vaccine stickers attached and syringes, with the logo of the University of Oxford and its partner British pharmaceutical company AstraZeneca, on November 17, 2020.

(Washington) —  Preliminary results from a study examining the efficacy of the Oxford-AstraZeneca coronavirus vaccine indicate it is significantly effective at preventing severe illness from COVID-19.

Results of the trial, which involved more than 32,000 volunteers, showed two doses of the vaccine administered four weeks apart had an efficacy of 79% at preventing symptoms of COVID-19. In participants aged 65 years and over, vaccine efficacy could be as high as 80%, AstraZeneca announced early Monday. It had an efficacy of 100% at preventing severe disease and hospitalization.

The results may mean the doses could soon be put into the arms of Americans. Data pulled from the study provides data to the Food and Drug Administration needed to grant the AstraZeneca vaccine an emergency use authorization. This approval would allow use of the vaccine by the general public to combat the coronavirus pandemic.

A nurse administers the Oxford AstraZeneca COVID-19 vaccine to a health worker on Jan. 30, 2021.

Abdeljalil Bounhar / AP Photo

A nurse administers the Oxford AstraZeneca COVID-19 vaccine to a health worker on Jan. 30, 2021.

AstraZeneca’s vaccine can be stored, transported and handled at normal refrigerated conditions (2-8 degrees Celsius or 36-46 degrees Fahrenheit) for at least six months. The company said it can also be administered without the need for preparation within existing healthcare settings.

The U.S. already has Pfizer, Moderna and Johnson & Johnson coronavirus vaccines distributed to the general public. But the Pfizer and Moderna vaccines must be stored at extremely cold temperatures, making shipping, storage and distribution difficult.

The Centers for Disease Control and Prevention report that as of Sunday 156,734,555 total vaccine doses have been distributed in the U.S. The agency reports 124,481,412 vaccine doses have been administered.

The vaccine is already being used around the world to prevent COVID-19. In recent weeks, several European countries temporarily suspended the use of the AstraZeneca vaccine following reports of blood clotting in at least 30 patients.

Most countries resumed using it, however, after the European Medicines Agency conducted an investigation and declared on Thursday that the AstraZeneca vaccine is safe and effective. The EMA said the benefits of the vaccine far outweigh the potential risks.

 

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