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Who faces the greatest risk of severe illness from coronavirus?

"This disease wasn't even known to us two months ago. So we're still learning a lot about specific risk factors for disease."

  • By Nell Greenfieldboyce/NPR
In this March 4, 2020 photo, two women wear masks as they ride a subway train, in New York. Two more cases of the new coronavirus have been confirmed in New York City, raising New York state's total to 13, Mayor Bill de Blasio said Thursday.

 Richard Drew / AP Photo

In this March 4, 2020 photo, two women wear masks as they ride a subway train, in New York. Two more cases of the new coronavirus have been confirmed in New York City, raising New York state's total to 13, Mayor Bill de Blasio said Thursday.

(Washington) — Anyone can catch COVID-19, the disease caused by the newly identified coronavirus. But certain populations appear to be more vulnerable to its effects.

Consider the 11 deaths so far in the United States — one in California and the rest in Washington state.

The person who died in Placer County, Calif., was described by officials as “an elderly adult with underlying health conditions.” Most of the people who died in Washington were residents of Life Care Center, a nursing facility in Kirkland. All but three of the victims in Washington were over age 70.

The younger people who died include one man in his 40s and two men in their 50s. Officials said these individuals had underlying medical problems that could have made them particularly susceptible to the virus, but officials would not detail what the problems were.

“There are too few patients to say specifically whether one underlying condition is more of a risk factor than another at this point,” said Dr. Jeff Duchin, a public health official for Seattle and King County who spoke at a press briefing on the outbreak in Washington on Monday.

“This disease wasn’t even known to us two months ago. So we’re still learning a lot about specific risk factors for disease,” he said.

Still, he said, public health workers do know enough to say, generally, what may make someone more susceptible.

A housekeeping worker wears a mask as she cleans a room, Wednesday, March 4, 2020, at an Econo Lodge motel in Kent, Wash. King County Executive Dow Constantine said Wednesday that the county had purchased the 85-bed motel south of Seattle to house patients for recovery and isolation due to the COVID-19 coronavirus.

Ted S. Warren / AP Photo

A housekeeping worker wears a mask as she cleans a room, Wednesday, March 4, 2020, at an Econo Lodge motel in Kent, Wash. King County Executive Dow Constantine said Wednesday that the county had purchased the 85-bed motel south of Seattle to house patients for recovery and isolation due to the COVID-19 coronavirus.

“It’s apparent from what’s been reported from China and from what we are seeing here locally that the patients who are having serious illness are those who are either very old, with weakened immune systems due to age, or have underlying chronic diseases,” said Duchin.

Those diseases include “chronic lung disease, chronic cardiac disease, diabetes,” he said, explaining that these are the same conditions that typically put people at greater risk of severe illness from seasonal influenza, another respiratory viral disease.

Much of what public health experts know about this virus comes from China, where the number of cases now tops 80,000.

There, children and younger people seem only mildly affected by the virus. A report from China described nine hospitalized children under 1 year old and found that none required intensive care or had any severe complications.

In China, where the outbreak originated, one study found that only 0.9% of 44,672 confirmed cases were in kids age 9 and under and that 1.2% were in youngsters age 10 to 19.

Most confirmed cases were among people age 30 to 79, and 80.9% of all illnesses were considered mild.

Estimates for the overall fatality rate for this coronavirus have varied, with one large study putting the figure at 2.3% in China. But that study found that in people age 80 or older, the death rate was much higher: 14.8%. Another study out of China that looked at the same 44,672 cases noted that the case fatality rate was 8% in patients age 70 to 79.

A sign on a shelf at a QFC grocery store in Kirkland, Wash., advises shoppers Tuesday, March 3, 2020 that all hand sanitizer products are sold out. Fear of the coronavirus has led people to stock up on the germ-killing gel, leaving store shelves empty and online retailers with sky-high prices set by those trying to profit on the rush. The store is located near the Life Care Center of Kirkland, which has been tied to several cases of the COVID-19 coronavirus.

Ted S. Warren / AP Photo

A sign on a shelf at a QFC grocery store in Kirkland, Wash., advises shoppers Tuesday, March 3, 2020 that all hand sanitizer products are sold out. Fear of the coronavirus has led people to stock up on the germ-killing gel, leaving store shelves empty and online retailers with sky-high prices set by those trying to profit on the rush. The store is located near the Life Care Center of Kirkland, which has been tied to several cases of the COVID-19 coronavirus.

Overall, the data coming out of China suggest that older people and people with underlying health conditions “were about twice as likely to develop serious outcomes [of COVID-19] versus otherwise younger, healthier people,” said Dr. Nancy Messonnier, director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention.

“We are particularly concerned about these people, given the growing number of cases in the United States,” she added in a press briefing on Tuesday.

It has long been recognized that people over 65 are at greater risk of developing severe complications from seasonal influenza. The CDC says that in recent years, between 70% and 85% of seasonal flu deaths have occurred in people age 65 and above.

Many of the same precautions taken for the flu should be taken to reduce the risk of coronavirus infections in this population, such as avoiding close contact with people who are sick and washing hands often.

“If you are 65 and older, and particularly if you live in areas where there is ongoing community spread,” says Messonnier, “you need to think about what actions you can take to reduce your exposure.”

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